Particles that carry cholesterol in the blood and around the body for use by cells. LDL-C is commonly known as “bad” cholesterol because high levels of LDL-C lead to increased risk of cardiovascular disease. Because most people with diabetes are at very high risk of heart disease, it is very important to achieve recommended LDL-C targets (2.0 mmol/L or lower for most people with diabetes). This usually requires medication.